Table 2.

Associations between principal components of oxidative stress and inflammation and AD biomarkers in the 40s.

	Dependent Variable:
	Tau		Aβ38 (log)		Aβ40 (log)		Aβ42 (log)		Aβ40/42
PC1	0.025	0.051	0.084 *	0.101 **	0.051 ***	0.059 ***	0.056 **	0.063 **	−0.005	−0.004
	p = 0.663	p = 0.399	p = 0.085	p = 0.050	p = 0.002	p = 0.0004	p = 0.026	p = 0.017	p = 0.701	p = 0.764
PC2	0.129	0.135	0.039	0.058	0.01	0.022	0.017	0.032	−0.007	−0.009
	p = 0.104	p = 0.101	p = 0.543	p = 0.385	p = 0.650	p = 0.313	p = 0.615	p = 0.368	p = 0.663	p = 0.595
PC3	0.03	0.018	0.198 **	0.193 **	0.104 ***	0.102 ***	0.136 ***	0.134 ***	−0.032	−0.033
	p = 0.767	p = 0.861	p = 0.019	p = 0.024	p = 0.0002	p = 0.0003	p = 0.003	p = 0.003	p = 0.147	p = 0.135
PC4	0.422 ***	0.445 ***	0.249 ***	0.235 ***	0.109 ***	0.110 ***	0.163 ***	0.168 ***	−0.054 **	−0.058 **
	p = 0.0001	p = 0.00005	p = 0.005	p = 0.010	p = 0.0002	p = 0.0002	p = 0.0004	p = 0.0004	p = 0.018	p = 0.013
Constant	4.825	5.8	8.421 **	9.627 **	5.978 ***	6.685 ***	3.712 *	4.584 **	2.266 **	2.101 **
	p = 0.286	p = 0.219	p = 0.025	p = 0.015	p = 0.00001	p = 0.00000	p = 0.055	p = 0.024	p = 0.019	p = 0.038
Observations	226	226	215	215	230	230	230	230	230	230
Log Likelihood	−429.823	−425.748	−361.794	−360.920	−137.188	−134.408	−242.856	−240.582	−81.986	−80.161
Akaike Inf. Crit.	875.647	877.497	739.588	747.84	290.375	294.817	501.711	507.163	179.971	186.322

Note: * p < 0.1; ** p < 0.05; *** p < 0.01.