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. 2022 May 26;10(6):1240. doi: 10.3390/biomedicines10061240

Table 3.

Associations between principal components of oxidative stress and inflammation and AD biomarkers in the 60s.

Dependent Variable:
Tau Aβ38 (log) Aβ40 (log) Aβ42 (log) Aβ40/42
PC1 −0.127 *** −0.142 *** −0.084 ** −0.099 *** −0.060 *** −0.065 *** −0.056 *** −0.060 *** −0.005 −0.005
p = 0.008 p = 0.005 p = 0.011 p = 0.004 p = 0.00001 p = 0.00001 p = 0.004 p = 0.003 p = 0.676 p = 0.679
PC2 −0.090 −0.081 0.038 0.04 −0.027 −0.028 −0.027 −0.029 −0.0005 0.002
p = 0.173 p = 0.227 p = 0.405 p = 0.392 p = 0.122 p = 0.123 p = 0.304 p = 0.268 p = 0.977 p = 0.912
PC3 −0.068 −0.076 −0.081 −0.082 −0.001 −0.001 −0.043 −0.043 0.042 ** 0.042 **
p = 0.375 p = 0.322 p = 0.131 p = 0.127 p = 0.945 p = 0.943 p = 0.154 p = 0.158 p = 0.023 p = 0.024
PC4 −0.316 *** −0.291 *** −0.151 *** −0.139 ** −0.035 −0.032 −0.061 * −0.060 * 0.026 0.029
p = 0.0002 p = 0.001 p = 0.010 p = 0.018 p = 0.113 p = 0.155 p = 0.061 p = 0.069 p = 0.181 p = 0.151
Constant 5.648 5.791 6.440 ** 7.137 ** 4.785 *** 5.219 *** 4.041 ** 4.840 *** 0.744 0.379
p = 0.220 p = 0.220 p = 0.044 p = 0.032 p = 0.0002 p = 0.00005 p = 0.027 p = 0.010 p = 0.496 p = 0.736
Observations 375 375 353 353 380 380 380 380 380 380
Log Likelihood −710.108 −706.354 −531.172 −528.038 −219.326 −216.888 −368.880 −366.495 −176.088 −174.311
Akaike Inf. Crit. 1436.215 1438.708 1078.345 1082.075 454.651 459.777 753.76 758.991 368.175 374.622

Note: * p < 0.1; ** p < 0.05; *** p < 0.01.