Table 2.

Multivariable conditional logistic regression analysis focused on the association between previous FQ use and FQ resistance in E. coli over a five-year period.

Variable	Adjusted OR (95% CI)	p
At least one FQ prescription in 1st previous year	2.67 (1.92–3.70)	<0.0001
At least one FQ prescription taken in previous 2nd year	1.54 (1.09–2.17)	0.015
At least one FQ prescription taken in previous 3rd, 4th or 5th year	1.09 (0.80–1.48)	0.997
Age	1.09 a (1.01–1.18)	0.026
Gender, male	1.42 (1.07–1.88)	0.016
Hospitalization days	1.03 b (1.01–1.06)	0.022
Diagnosis of chronic diseasesDiabetes	1.41 (0.96–1.80)	0.037
COPD	1.43 (1.05–1.87)	0.019

^a OR calculated for 10-year increments; ^b OR calculated for 10-day increments. Abbreviations: FQ = fluoroquinolone, COPD = chronic obstructive pulmonary disease.