Table 8.
Biomarkers associated with DNA, RNA and miRNA.
| BIOMARKER | SAMPLE | CUT VALUES (FRAIL—NOT FRAIL) | FRAILTY SCALE | COUNTRY | YEAR | GROUP DESCRIPTION |
REFERENCE |
|---|---|---|---|---|---|---|---|
| miR-10a-3p | Plasma | Increased in frailty | Fried | United States | 2018 | Young people (ages 23–35 years) and people older than 65 years were recruited (the latter were classified as frail or not frail according to Fried’s criteria). | Ipson, B.R., et al. (2018) [167] |
| miR-92a-3p | Plasma | Increased in frailty | Fried | United States | 2018 | Young people (ages 23–35 years) and people older than 65 years were recruited (the latter were classified as frail or not frail according to Fried’s criteria) | Ipson, B.R., et al. (2018) [167] |
| miR-185–3p | Plasma | Increased in frailty | Fried | United States | 2018 | Young people (ages 23–35 years) and people older than 65 years were recruited (the latter were classified as frail or not frail according to Fried’s criteria) | Ipson, B.R., et al. (2018) [167] |
| miR-194–5p | Plasma | Increased in frailty | Fried | United States | 2018 | Young people (ages 23–35 years) and people older than 65 years were recruited (the latter were classified as frail or not frail according to Fried’s criteria) | Ipson, B.R., et al. (2018) [167] |
| miR-326 | Plasma | Increased in frailty | Fried | United States | 2018 | Young people (ages 23–35 years) and people older than 65 years were recruited (the latter were classified as frail or not frail according to Fried’s criteria) | Ipson, B.R., et al. (2018) [167] |
| miR-532–5p | Plasma | Increased in frailty | Fried | United States | 2018 | Young people (ages 23–35 years) and people older than 65 years were recruited (the latter were classified as frail or not frail according to Fried’s criteria) | Ipson, B.R., et al. (2018) [167] |
| miR-576–5p | Plasma | Increased in frailty | Fried | United States | 2018 | Young people (ages 23–35 years) and people older than 65 years were recruited (the latter were classified as frail or not frail according to Fried’s criteria) | Ipson, B.R., et al. (2018) [167] |
| miR-760 | Plasma | Increased in frailty | Fried | United States | 2018 | Young people (ages 23–35 years) and people older than 65 years were recruited (the latter were classified as frail or not frail according to Fried’s criteria) | Ipson, B.R., et al. (2018) [167] |