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Mitochondrial bioenergetics in C9ALS/FTD patients and the control samples. VDAC protein content was quantified by Western blot and represented as a ratio of β-actin content. The results are expressed as means ± standard error of the mean (SEM). Although not statistically significant, fibroblasts from C9ALS/FTD patients showed a 2-fold increase in VDAC content at basal conditions and after bafilomycin treatment (4 h and 8 h).
