Table 1.
Minimal inhibitory concentrations (MICs) of Pseudocitrobacter faecalis clinical isolate, transformant, and recipient.
| Strains | β-Lactamase Genes | Fluoroquinolone- Resistant Genes |
MIC (mg/L) a | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IMP | MEM | CAZ | FEP | ATM | CZA | SCF | TZP | SXT | CIP | LEV | AMK | TGC | POL | |||
| P. faecalis SC48 | blaDHA-1, blaOXA-1, blaOXA-181 | qnrB4, qnrS1, aac(6’)-Ib-cr | 64 | 32 | 2 | 8 | ≤1 | 1 | 128 | >256 | 0.5 | >8 | 8 | 4 | 1 | 0.5 |
| P. faecalis SC62 | blaDHA-1, blaOXA-1, blaOXA-181 | qnrB4, qnrS1, aac(6’)-Ib-cr | 64 | 64 | 2 | 8 | ≤1 | 1 | 128 | >256 | 0.5 | >8 | 8 | 8 | 1 | 0.5 |
|
E. coli DH5α- SC48-T |
bla OXA-181 | qnrS1 | 1 | 0.25 | 0.5 | 0.125 | ≤1 | 0.25 | 8 | 64 | ≤0.25 | 0.25 | 0.5 | ≤1 | 0.25 | 0.25 |
| E. coli DH5α | - | - | 0.125 | ≤0.03 | 0.5 | ≤0.06 | ≤1 | 0.125 | ≤1 | 4 | ≤0.25 | ≤0.06 | ≤0.125 | ≤1 | 0.125 | 0.25 |
a IPM, imipenem; MEM, meropenem; CAZ, ceftazidime; FEP, cefepime; ATM, aztreonam; CZA, ceftazidime-avibactam; SCF, cefoperazone-sulbactam; TZP, piperacillin-tazobactam; SXT, trimethoprim-sulfamethoxazole; CIP, ciprofloxacin; LEV, levofloxacin; AMK, amikacin; TGC, tigecycline; POL, polymyxin B.