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. 2022 May 28;11(6):1074. doi: 10.3390/antiox11061074

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The “speed” by which CRCs and DMCRT reduce cell viability. CRCs manifested a dose-dependent effect from 0–2.857 mg/mL, indicating that the induced “damage” was time dependent. The 5.174 and 11.429 mg/mL concentrations showed that probably all effects were already induced at 24 h and time did not play a role thereafter (A). Similarly, DMCRT manifested a dose-dependent increase in “velocity” yet it reached a plateau after 2.857 mg/mL, indicating that its effects were mostly time-dependent in all cases (B) (Legend: CRCs: Crocins, DMCRT: dimethylocrocetin).