Table 2.

IsomiR-related genes and human diseases.

isomiR-Related Genes	Human Diseases	Reference
DICER1	pleuropulmonary blastoma familial tumor predisposition syndrome (G)	[106]
DROSHA	ovarian cancer (S)	[107]
TUT1	retinitis pigmentosa (U)	[108]
TUT4, TUT7	Perlman syndrome (U)	[109]
PARN	dyskeratosis congenita (G)	[110]
ADAR	dyschromatosis symmetrica hereditaria (G)	[111]
APOBEC	bladder cancer (U)	[112]
METTL3	acute myeloid leukemia (S)	[113]

G, germline mutations; S, somatic mutations; U, unknown.