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. 2022 Jun 8;11(6):880. doi: 10.3390/biology11060880

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Sham-operated and (B) 8-week aortic banded rats at same magnification. Note increased size and variable cross-sectional area in the banded rat. Methacrylate embedded, 1 µm section, silver stain. Bar = 50 µm for both A and B. (C) Patient with old ischemic infarct. Note marked variability in hypertrophied LV myocytes. Masson trichrome stain. Bar = 20 µm. (Bottom row) Scanning electron micrographs of isolated myocytes from hypertrophied LV of aortic banded rats. Note extreme variability in size and shape, grooves for capillaries.