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. 2022 Jun 9;11(6):1137. doi: 10.3390/antiox11061137

Figure 2.

Figure 2

Effects of miR-181b mimics and inhibitor on vascular function. (A,B) Wire myography on EDRs of aortic rings from normal chow-fed mice and HFD/STZ-induced diabetic mice, upon (A) transfection of miR-181b mimics or (B) treatment with AICAR. (C,D) Wire myography on SNP-induced endothelium-independent relaxations of aortic rings from normal chow-fed mice and HFD/STZ-induced diabetic mice, upon (C) transfection of miR-181b mimics or (D) treatment with AICAR. n = 6 per group. Data are mean ± SD. * p < 0.05 (Brown-Forsythe and Welch ANOVA and Games–Howell’s multiple comparisons).