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Effects of miR-181b mimics and inhibitor on vascular and endothelial inflammation. RT-PCR on expression of inflammatory markers (A) Icam1, (B) Vcam1, and (C) Il-6 in aortas of normal chow-fed and diabetic mice. RT-PCR on expression of inflammatory markers (D) ICAM1, (E) VCAM1, and (F) IL-6 in HUVECs treated with 200 μg mL−1 AGEs for 12 h. n = 6 per group. Data are mean ± SD. * p < 0.05 (Brown-Forsythe and Welch ANOVA and Games-Howell’s multiple comparisons).
