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Two out of the 15 mutations, namely (A) Y505H, (B) K417 N presented with a ΔΔG value above and below zero respectively. Blue boxes indicate Omicron (left) and orange boxes indicate Wuhan (right). The interface between RBD (blue) and ACE2 (red) is shown (Interaction colors: Hydrogen Bond (Red), Hydrophobic (Green), Polar (Orange), van der Waals (Blue)).
