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. 2022 Jun 17;11(6):817. doi: 10.3390/antibiotics11060817

Table 7.

Carcinogenic potential via TOPKAT (Rat TD50 and RMTD).

Compound Rat TD50
(mg/kg Body Weight/Day)
RMTD—Feed
(mg/kg Body Weight/Day)
Clarithromycin 0.002 9.995
Diclofenac 51.448 742.520
Ellagic Acid 5.838 721.906

Abbreviations: RMTD: rat maximum tolerated dose; TD50: tumorigenic dose rate.