Table 1.
Top 30 downregulated genes in Fusarium-infected HCFs based on fold-change compared to uninfected controls.
| Gene | Description | Fold change | p value |
|---|---|---|---|
|
| |||
| EAPP | E2F-associated Phosphoprotein that promotes proliferation | − 27.9098 | .00005 |
| CDC123 | Cell Division Cycle 123 protein required for entry into S phase | − 18.3722 | .00005 |
| AKR1C3 | Aldo-keto reductase family 1 member C3 | − 15.7936 | .00005 |
| TXNDC9 | Thioredoxin domain-containing protein involved in proliferation | − 15.4993 | .00005 |
| C10orf10 | also called DEPP1 involved in regulating autophagy | − 13.1128 | .00005 |
| AKR1B10 | Aldo-keto reductase family 1 member B10 | − 11.5138 | .00005 |
| AHNAK2 | Nucleoprotein | − 10.5996 | .00005 |
| ADH1B | Alcohol dehydrogenase 1 B | − 9.87931 | .00005 |
| TSEN15 | tRNA splicing endonuclease | − 9.86378 | .00005 |
| PSMB6 | Proteasome subunit beta type-6 | − 9.78533 | .00005 |
| TSNAX | Translin Associated Factor X involved in activation of the RNA-induced silencing complex | − 9.56424 | .00005 |
| ABHD10 | Abhydrolase Domain Containing 10 | − 9.54715 | .00005 |
| EHD3 | EH Domain Containing 3 | − 9.48107 | .00005 |
| TXNIP | Thioredoxin Interacting Protein | − 9.01758 | .00005 |
| FIBIN | Fin Bud Inititation Factor | − 8.98376 | .00005 |
| SLC1A5 | Soluble Carrier Family 1 Member 3 encodes a sodium-dependent neutral amino acid transporter | − 8.91757 | .00005 |
| CBR1 | Carbonyl reductase 1 | − 8.45052 | .00005 |
| GAS1 | Growth Arrest Specific 1 involved in growth suppression | − 8.31952 | .00005 |
| ZFYVE21 | Zinc Finger FYVE-Type Containing 21 involved in cell adhesion | − 8.15068 | .00005 |
| TRAPPC1 | Trafficking Protein Particle Complex 1 involved in ER to Golgi transport | − 8.1408 | .00005 |
| THYN1 | Thymocyte Nuclear Protein 1 potentially involved in the induction of apoptosis | − 8.07952 | .00005 |
| PITX2 | Paired Like Homeodomain 2 encoding a transcription factor that regulates eye development |
− 7.90015 | .00005 |
| TNRC18 | Trinucleotide Repeat Containing 18 | − 7.81345 | .00005 |
| UQCR10 | Ubiquinol-Cytochrome C Reductase involved in respiratory metabolism | − 7.60601 | .00005 |
| PSAT1 | Phosphoserine Aminotransferase 1 | − 7.57891 | .00005 |
| MRPS17 | Mitochondrial Ribosomal Protein S17 | − 7.52802 | .00005 |
| LRIG3 | Leucine Rich Repeats and Immunoglobulin Like Domain | − 7.36012 | .00005 |
| ZFHX4 | Zinc Finger Homeobox 4 | − 7.2105 | .00005 |
| PREB | Prolactin Regulatory Element-Binding Protein | − 7.18451 | .00005 |
| FBXO38 | F-Box Protein 38 | − 7.18292 | .00005 |