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. Author manuscript; available in PMC: 2022 Jun 23.
Published in final edited form as: Exp Eye Res. 2021 Apr 15;207:108581. doi: 10.1016/j.exer.2021.108581

Table 4.

KEGG analysis of the 396 upregulated genes in Fusarium-infected HCFs.

Name p- value Genes

IL-17 A Signaling 3.53e-17 HSP90AB1,MAPK6,TRAF4,CEBPB, JUND, CXCL6,MMP3,JUN, NFKB1,HSP90AA1,CXCL5,FOS,FOSL1, PTGS2,IL1B,MMP1, NFKBIA, CXCL1,IL6,FOSB, TNFAIP3,CXCL3, CXCL2,CSF3,CXCL8
TNF Signaling 4.93e-16 FAS,MAP2K3,CSF1,CEBPB,MAP3K8,
ICAM1,CREB5,CXCL6,MMP3,JUNB,IRF1,
JUN,NFKB1,TRAF1,CXCL5,FOS,PTGS2, IL1B,NFKBIA, CXCL1,LIF,BIRC3,IL6,TNFAIP3,CXCL3, CXCL2
NFκB Signaling 5.97e-8 TICAM1,PLAU, CYLD,ICAM1,NFKB2,RELB, NFKB1,TRAF1,PTGS2, GADD45B,IL1B,NFKBIA, CXCL1,BIRC3, TNFAIP3,CXCL3,CXCL2, CXCL8
MAPK Signaling 1.45e-12 HSPA8,FAS,MAP2K3,GADD45A, MAPKAPK2,CSF1,PPP3CC, HSPB1,DUSP10,VEGFA,MAP3K8,JUND, PLA2G4C,NFKB2,RELB, JUN,DUSP1,NFKB1,DUSP5,FOS,GADD45B, NR4A1,DUSP8,EREG, IL1B,IL1A,HSPA1B,HSPA1,HSPA6
C-type Lectin Receptor Signaling 7.18e-6 MAPKAPK2,CBLB,PLK3,PPP3CC,CYLD, EGR3,NFKB2,IRF1,RELB, JUN,NFKB1,PTGS2,IL1B,NFKBIA,IL6
Cytokine-cytokine Receptor Interaction 6.06e-5 FAS,ACKR3,CSF1,TNFRSF10B,CLCF1, TNFRSF12A,INHBA,IL6R,CXCL6,IL32,IL7, RELT, CXCL5,GDF15,IL1B,CXCL1,IL1A,LIF, IL6,IL11,CXCL3,CXCL2,CSF3,CXCL8
Th17 Cell Differentiation 2.89e-4 HSP90AB1,PPP3CC,RORA, NFKBIB,IL6R, JUN,NFKB1,HSP90AA1,NFKBIE,FOS,IL1B, NFKBIA,IL6
NOD-like Receptor Signaling Pathway 3.35e-4 HSP90AB1,TICAM1,NFKBIB, NAMPT, RIPK2,JUN,NFKB1, HSP90AA1,IL1B,NFKBIA, CXCL1,BIRC3,IL6, TNFAIP3,CXCL3, CXCL2,CXCL8
Apoptosis 5.45e-3 FAS,GADD45A,MCL1,ERN1,TNFRSF10B, JUN,NFKB1,PMAIP1, TRAF1,FOS,GADD45B,NFKBIA, BIRC3
Circadian Rhythm 1.27e-2 NR1D1,RORA, BHLHE41,PER1,CRY1, BHLHE40
Cellular Senescence 2.50e-2 MAP2K3,GADD45A,MAPKAPK2,PPP3CC, SIRT1,RASSF5,NFKB1,ETS1,SERPINE1, GADD45B,IL1A,IL6,CXCL8
Toll-like Receptor Signaling Pathway 3.22e-2 MAP2K3,TICAM1,MAP3K8,JUN,NFKB1, FOS,IL1B,NFKBIA,IL6, CXCL8