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. 2022 May 25;10(6):1234. doi: 10.3390/biomedicines10061234

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Structural organization of KDELR. The images show the side (A) and top view (B) of Gallus gallus KDELR2 according to the PDB database coordinates (PDB DOI: 10.2210/pdb6ZXR/pdb 27 April 2022). The two helical bundles made up of the first three and last three helices are shown in light green and light blue, respectively. The fourth transmembrane helix, which connects the two bundles, is shown in light brown. The RDEL ligand, represented in sticks, is located in the pocket formed by the TM1-3 and TM5-7 helices.