Table 10.

Validation of the M20-13-6 model in the prediction of cartilage volume loss at one year in 12 cartilage regions using five bone curvature regions at the baseline.

Outcome	Man			Woman
	R	RMSE	MAE	R	RMSE	MAE
Global knee	0.89	0.018	0.015	0.89	0.022	0.016
Global femur	0.90	0.019	0.015	0.84	0.026	0.017
Global condyle	0.85	0.023	0.018	0.81	0.032	0.019
Global tibial Plateau	0.88	0.027	0.020	0.79	0.032	0.028
Lateral compartment	0.94	0.021	0.016	0.86	0.022	0.017
Lateral femur	0.92	0.021	0.016	0.83	0.027	0.018
Lateral condyle	0.96	0.026	0.018	0.86	0.031	0.020
Lateral tibial plateau	0.94	0.040	0.023	0.87	0.028	0.023
Medial compartment	0.87	0.027	0.021	0.90	0.031	0.023
Medial femur	0.88	0.027	0.022	0.89	0.030	0.021
Medial condyle	0.91	0.026	0.021	0.87	0.037	0.027
Medial tibial plateau	0.78	0.041	0.029	0.47	0.062	0.045

The model was validated using osteoarthritis patients from a clinical trial cohort (Naproxen). R, correlation coefficient; RMSE, root mean square error; MAE, mean absolute error.