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. 2022 Jun 13;10(6):1400. doi: 10.3390/biomedicines10061400

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The expression profile of genes was associated with apoptosis and cell survival. Transcript levels were established for CRSwNP patients to the healthy subjects. The following markers at mRNA were detected: BAX—apoptosis regulator BCL2 Associated X (A); BCL-2—B-cell CLL/lymphoma 2 (B); P53—Tumor Protein P53 (C); P21—cyclin-dependent kinase inhibitor 1A (D); BIRC5—Baculoviral IAP repeat-containing protein 5 (E); CASP3—Caspase 3 (F); CASP9—Caspase 9 (G); APAF1—Apoptotic protease-activating factor 1 (H); CCND1—G1/S-specific cyclin-D1 (I); cMYC—Myc proto-oncogene protein (J). The average fold change of the target genes was determined in relation to the housekeeping gene, i.e., glyceraldehyde 3-phosphate dehydrogenase (GAPDH). Statistically, significant differences are indicated with an asterisk. Statistically significant differences were noted at p < 0.01 (**), and p < 0.001 (***).

The expression profile of genes was associated with apoptosis and cell survival. Transcript levels were established for CRSwNP patients to the healthy subjects. The following markers at mRNA were detected: BAX—apoptosis regulator BCL2 Associated X (A); BCL-2—B-cell CLL/lymphoma 2 (B); P53—Tumor Protein P53 (C); P21—cyclin-dependent kinase inhibitor 1A (D); BIRC5—Baculoviral IAP repeat-containing protein 5 (E); CASP3—Caspase 3 (F); CASP9—Caspase 9 (G); APAF1—Apoptotic protease-activating factor 1 (H); CCND1—G1/S-specific cyclin-D1 (I); cMYC—Myc proto-oncogene protein (J). The average fold change of the target genes was determined in relation to the housekeeping gene, i.e., glyceraldehyde 3-phosphate dehydrogenase (GAPDH). Statistically, significant differences are indicated with an asterisk. Statistically significant differences were noted at p < 0.01 (**), and p < 0.001 (***).