Table 6.

Differences between genotypes concerning the psychometry, peripheral serotonin content, and serotonergic activity in patients and healthy participants.

	Patients		Healthy Participants
	LL	LS/SS	LL	LS/SS
Psychometry
HAMD-21 a (mean ± SD) (n)	17.94 ± 6.60 (32)	18.91 ± 4.27 (57)	1.50 ± 1.88 (26)	1.48 ± 2.06 (63)
t-test	t(45.87) = 0.753; p = 0.456		t(87) = −0.051; p = 0.960
BDI-II d (mean ± SD)	34.53 ± 10.05 (32)	32.53 ± 10.70 (57)	3.27 ± 3.04 (26)	4.06 ± 5.76 (63)
t-test	t(87) = −0.867; p = 0.389		t(87) = 0.664; p = 0.508
STAI-X1 b (mean ± SD)	54.56 ± 12.87 (32)	55.81 ± 12.12 (57)	31.88 ± 6.49 (26)	33.92 ± 8.49 (63)
t-test	t(87) = 0.455; p = 0.651		t(87) = 1.10; p = 0.276
STAI-X2 c (mean ± SD)	59.75 ± 11.12 (32)	61.02 ± 7.99 (57)	31.69 ± 6.73 (26)	33.03 ± 7.40 (63)
t-test	t(49.32) = 0.568; p = 0.573		t(87) = 0.797; p = 0.428
Serotonin content
Platelet serotonin content(109/Thr) (mean ± SD) (n)	1139.26 ± 994.50 (27)	1098.65 ± 956.40 (45)	2164.42 ± 1016.54 (22)	1940.30 ± 1033.37 (50)
t-test	t(70) = −0.172; p = 0.864		t(70) = −0.852; p = 0.397
Serum serotonin content(ng/mL) (mean ± SD) (n)	252.54 ± 354.20 (32)	231.10 ± 323.11 (56)	734.77 ± 594.87 (26)	788.03 ± 665.39 (62)
t-test	t(86) = −0.289; p = 0.773		t(86) = 0.353; p = 0.725
Serotonergic activity
Cortical LDAEP (mean ± SD) (n)	0.278 ± 187 (24)	0.242 ± 0.186 (42)	0.234 ± 0.132 (19)	0.256 ± 0.116 (47)
t-test	t(64) = −0.744; p = 0.459		t(64) = 0.690; p = 0.496
Source LDAEP (left) (mean ± SD) (n)	0.217 ± 0.195 (24)	0.201 ± 0.209 (42)	0.211 ± 0.145 (19)	0.299 ± 0.601 (47)
t-test	t(64) = −0.299; p = 0.766		t(64) = 0.630; p = 0.531
Source LDAEP (right) (mean ± SD) (n)	0.227 ± 0.250 (24)	0.171 ± 0.243 (42)	0.177 ± 0.255 (19)	0.284 ± 0.568 (47)
t-test	t(64) = −0.894; p = 0.374		t(64) = 0.789; p = 0.433

^a Hamilton = HAMD-21; ^b State Anxiety Inventory = STAI-X1; ^c Trait Anxiety Inventory = STAI-X2; ^d Beck Depression Inventory = BDI-II.