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GDE-enhanced anxiety-like behaviors in adult male and female mice. Anxiety-like behavior in the elevated plus maze was calculated by determining the percentage of open arm entries (a), the percentage of open arm time (b), and closed arm entries (c) for adult males and females. Error bars, SEM (* p < 0.05 vs. GDS male group, # p < 0.05 vs. GDS female group; n = 8 mice/group).
