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. 2022 May 31;12(6):726. doi: 10.3390/brainsci12060726

Table 2.

Smallest Detectable Change (SDC) and Standard Error of Measurement (SEM) for Tinnitus Functional Index (TFI/TFI-22) scores between three administrations.

Mean (±SD) Difference Measurement Error
Scale n T0 T1 T2 Mean Diff SD Diff SEM SEM × 4 SDC
TFI-25 50 50.8 (±25.1) 45.9 (±22.8) 44.9 (±23.1) −5.4 7.2 5.1 20.4 14.2
TFI-22 50 51.3 (±25.9) 45.7 (±23.3) 45.0 (±23.7) −5.9 7.1 5.0 20.0 13.9
INT 46 64.0 (±24.3) 55.6 (±23.2) 54.7 (±23.3) −9.8 13.2 9.3 37.2 25.8
SOC 48 61.9 (±24.3) 56.5 (±24.2) 55.0 (±24.0) −6.2 10.7 7.6 30.4 21.0
COG 49 40.9 (±28.4) 39.3 (±27.2) 38.0 (±26.0) −2.2 13.5 9.6 38.4 26.5
SLP 48 52.6 (±32.0) 46.4 (±29.2) 47.1 (±29.4) −4.8 13.3 9.4 37.6 25.9
AUD 50 47.7 (±30.1) 47.5 (±28.8) 44.4 (±28.2) −1.7 16.2 10.7 42.8 29.6
REL 50 62.0 (±29.3) 55.9 (±26.4) 53.5 (±27.4) −7.4 14.4 10.2 40.8 28.3
QOL 49 38.6 (±32.4) 34.7 (±28.9) 33.3 (±29.0) −4.6 11.3 8.0 32.0 22.2
EMO 50 42.8 (±31.5) 35.7 (±29.7) 38.4 (±30.2) −5.7 14.6 10.3 41.2 28.6

T0 = Baseline, T1 = 3-month follow-up, T2 = 6-month follow-up; Mean diff = the mean difference scores between administrations; SD diff = Standard Deviation of the difference; SEM = Standard Error in Measurement (SDdiff/√2); SDC = Smallest Detectable Change (1.96 × √2 × SEM). For subscale definitions, please refer to Table 1.