Table 1.
Comparison of non-specific combinations of AuNPs with conventional PCR product.
| Detection Method | Strategy | Target | Detection Limit | Aggregation Time | Ref. |
|---|---|---|---|---|---|
| Colorimetric | ssDNA adsorbs on AuNPs without amplification. | Genomic DNA | — | Less than 1 min | [46] |
| Colorimetric | As-PCR ssDNA product bound to naked AuNPs. | Long genomic ssDNA | Picogram detection level | 10 min | [49] |
| Colorimetric | PMA selectively intercalates DNA in dead cells. | Live emetic Bacillus cereus DNA | 3.4 × 102 CFU/mL | — | [60] |
| Colorimetric | Non-specific interactions between AuNPs and PCR products | Prostate cancer urinary biomarker PCA3 | 31.25 ng/reaction | — | [62] |