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. 2022 May 25;12(6):747. doi: 10.3390/biom12060747

Table 2.

A 2 × 3 contingency table of CI state (negative/positive) by α-syn inclusion (LB or PB/punctate inclusions/no inclusion).

Cytoplasmic α-syn Inclusion Total
LB/PB Punctate No Inclusion
O1 O2 O1 O2 O1 O2 O1 O2
CI state CI+ Count 23 18 28 31 125 146 176 195
Expected count 20.9 16.6 34.5 35.9 120.7 142.6
% Within CI state 14.0 9.2 15.9 15.9 71.0 74.9
Adjusted residual 1.6 1.3 −4.0 −3.2 2.3 2.0
CI− Count 0 0 10 8 8 9 18 17
Expected count 2.1 1.4 3.5 3.1 12.3 12.4
% Within CI state 0.0 0.0 55.6 47.1 44.4 52.9
Adjusted residual −1.6 −1.3 4.0 3.2 −2.3 −2.0
p-value 0.11 0.19 6.3 × 10−5 1.3 × 10−3 0.021 0.046
Total 23 18 38 39 133 155 194 212

α-syn: α-synuclein; LB: Lewy body; PB: pale body; Punctate: punctate inclusions; O1: observer 1; O2: observer 2; CI+: CI-positive neuron; CI−: CI-negative neuron.