Figure 4. Longitudinal assessment of clonal depth and breadth.
(A and B) Clonal breadth (A) and depth (B) for COVID cases (n = 86) at 2 months and 9 months. The dotted line indicates the line y = x. Spearman’s correlations are indicated by ρ and corresponding P values by P. (C–F) Mean clonal breadth and mean clonal depth of T cells specific to spike protein are shown across time, while E depicts mean clonal breadth and F depicts mean clonal depth of T cells specific to non-spike proteins across time. The shaded areas represent the 95% CI of the mean. Samples were grouped by vaccination status at month 15.