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. 2022 Jun 8;7(11):e149741. doi: 10.1172/jci.insight.149741

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© 2022 Chyu et al.

This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Detection of ApoB_KTTKQSFDL pentamer ⁺ cells in splenocytes of A2Kb-Tg ApoE^–/– mice 13 weeks after second booster injection with either PBS or P210-PAM; ^†P = 0.08, 2-tailed t test. (B) Representative photographs of aortic atherosclerosis in these mice. (C) Measurement of percentage aortic atherosclerosis area. (D) Representative photographs of aortic atherosclerosis in a second cohort of mice immunized with either MSA-PAM or P210-PAM. (E) Percentage aortic atherosclerosis area measurement. *P < 0.05, 2-tailed t test.