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. 2022 May 23;7(10):e159090. doi: 10.1172/jci.insight.159090

Figure 2. Circulating viral RNA and infectious virus titers from SUDV-challenged rhesus macaques.

Figure 2

Viral load was determined by RT-qPCR of whole blood (A, C, E, and G) or plaque titration of plasma (B, D, F, and H). (A and B) Treatment at 5 dpi with remdesivir, (C and D) treatment at 6 dpi with remdesivir, (E and F) treatment at 6 dpi with MBP431, (G and H) treatment at 6 dpi with combined remdesivir/MBP431. For all panels, individual data points represent the mean of 2 technical replicates. Dashed horizontal lines indicate the limit of detection (LOD) for the assay (1000 GEq/mL for RT-qPCR; 25 PFU/mL for plaque titration). To fit on a log-scale axis, zero values (below LOD) are plotted as “1” (100).