Table 1.
List of mutant peptides identified in HCT116 cells.
| Sequence | HLA | IC50 (nM) | Mutation Locus | Gene | Protein | AA Change | Wild Peptides Identified | Reference |
|---|---|---|---|---|---|---|---|---|
| QTDQMVFNTY | HLA-A*01:01 | 15.85 | chr8:23258741 | CHMP7 | Q8WUX9 | p.A324T | Yes | [25,48,53,54] |
| RLDPGEPKSY | HLA-A*01:01 | 1193.67 | chr9:35750732 | RGP1 | Q92546 | p.S110P | No | [53] |
| AAAPVVPQV | HLA-A*02:01 | 175.14 | chr6:149796499 | PCMT1 | P22061 | p.A168V | No | [53] |
| DEQQVDVL | HLA-B*18:01 | 771.4 | chr20:31605574 | ID1 | P41134 | p.N63D | Yes | - |
| EEEYPGVTA | HLA-B*45:01 | 106.68 | chr22:17726722 | BCL2L13 | Q9BXK5 | p.I216V | Yes | [48] |
| EEYPGVTA | HLA-B*45:01 | 448.13 | chr22:17726722 | BCL2L13 | Q9BXK5 | p.I216V | No | - |
| SLFNKYPAL | HLA-A*02:01 | 11.61 | chrX:115643440 | PLS3 | P13797 | p.N372S | No | - |
| FLDNQQHGM | HLA-C*05:01 | 20.86 | chr1:88804485 | PKN2 | Q16513 | p.R459Q | No | - |
HLA, human leukocyte antigen; AA, amino acid.