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. 2022 May 23;7(10):e157053. doi: 10.1172/jci.insight.157053

Figure 2. Left ventricular ejection fraction, left ventricular mass index, and diastolic function by cardiopulmonary symptoms.

Figure 2

(A) Box plot of left ventricular (LV) ejection fraction (LVEF) by symptoms, (B) box plot of LV mass index by symptoms, and (C) diastolic function by symptoms (n = 101, 99, and 101, respectively). Odds of symptoms were 1.16 times higher per 5% decrease in LVEF, which was not statistically significant (95% CI, 0.83–1.62; P = 0.40). The odds of symptoms were not significantly higher with increased LV mass (1.01 per 5 g/m2; 95% CI, 0.89–1.16; P = 0.81). With regards to diastolic function, 7% of those without symptoms and 11% with symptoms had mild diastolic dysfunction; the odds of symptoms were 1.77 times higher among those with diastolic dysfunction compared with those with normal diastolic function, which was not statistically significant but could not exclude a meaningful effect (95% CI, 0.35–8.88; P = 0.78), especially because there were no participants with more than mild diastolic dysfunction. In A and B, boxes represent the 25th and 75th percentile, the lines inside the boxes represent medians, whiskers represent the upper and lower adjacent values (3/2 times the IQR from the end of the box) as defined by Tukey, and dots represent outliers outside the whiskers.