Figure 1.

Mitochondrial respiratory function in the cortex and cerebellum. Data presented as median and interquartile range with individual data points (black dots) for respiratory rates relative to citrate synthase (CS) activity in the cortex (A) and cerebellum (B) for leak respiration (CI_L), Complex I-linked respiration (CI_P), CI&CII-linked respiration (CI&CII_P) and CII_P-linked respiration (CII_P), leak state, oxidative phosphorylation (OXPHOS) coupling efficiency, the fraction of OXPHOS capacity attributable to CI and the fraction of OXPHOS capacity attributable to CII (CI and CII flux control ratios) from saline (open columns, n = 7) and cortisol-infused (filled columns, n = 6) fetuses at ~130 days of gestational age (dGA). * Significantly different from saline control, p < 0.05, t-test. One data point (Complex I Flux Control Ratio, control fetus) was detected as an outlier according to the ROUT method [18] and was removed from subsequent analysis.