Table 3.
Multivariate regression showing the effect of education, age, UPDRSIII drug off, UPDRSIII drug on, MoCA Preop, MMSE Preop and drug improvement rate on the improvement rate of cognitive state.
| Non-Adjusted | Model I | Model II | ||||
|---|---|---|---|---|---|---|
| OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | |
| Education (years) | 1.42 (1.23, 1.63) | *** | 1.44 (1.23, 1.68) | *** | 1.49 (1.25, 1.77) | *** |
| Age (years) | 1.06 (1.00, 1.11) | * | 1.09 (1.01, 1.17) | * | 1.07 (0.99, 1.15) | |
| UPDRSIII drug off | 1.04 (1.01, 1.07) | ** | 1.05 (1.01, 1.09) | ** | 1.04 (1.00, 1.08) | |
| UPDRSIII drug on | 1.08 (1.03, 1.12) | *** | 1.09 (1.03, 1.14) | ** | 1.08 (1.02, 1.14) | ** |
| MoCA Preop | 0.46 (0.34, 0.64) | *** | 0.16 (0.05, 0.54) | ** | 0.14 (0.04, 0.54) | ** |
| MMSE Preop | 0.70 (0.61, 0.82) | *** | 0.60 (0.48, 0.75) | *** | 0.61 (0.49, 0.77) | *** |
| Drug improvement rate | 0.04 (0.00, 0.79) | * | 0.03 (0.00, 0.77) | * | 0.04 (0.00, 1.15) |
Model I is adjusted for duration and gender, whereas Model II is adjusted for duration, gender, H-Y, LED, NMSS Preop, PDQ39 Preop. CI, confidence interval; OR, odds ratio. * p < 0.05 ** p < 0.01 *** p < 0.001.