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. 2022 May 23;7(10):e157035. doi: 10.1172/jci.insight.157035

Figure 1. Manhattan plot of GWAS of antibody-based and aptamer-based circulating uromodulin.

Figure 1

The plots represent, for each SNP, the P value from meta-analyses of GWAS of antibody-based (n = 13,985, dark blue, A) and of aptamer-based circulating uromodulin (n = 18,070, light blue, B). The x axis shows chromosomal location and the y axis the –log10(P value) of SNP associations with circulating uromodulin. The plots were generated using the R package EasyStrata v8.6. Meta-analyses of X chromosomal markers did not yield any significant findings.