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. 2022 Jun 8;7(11):e155482. doi: 10.1172/jci.insight.155482

Figure 15. Nonclassical monocyte gene expression clusters by GA.

Figure 15

Nonclassical monocytes (n = 24) divided into 2 major hierarchical cluster. One cluster was composed primarily of samples obtained from preterm deliveries with MVM on placental pathology (Group A). The second cluster contained samples from term deliveries with presumed normal placental pathology (Group B). Based on DeSeq2, 1938 genes were differentially expressed using FDR < 0.05 and 2-fold change. There were 2 major gene clusters based on k-means clustering. The genes in Cluster B were upregulated in Group A, and these genes were related to leukocyte adhesion to vascular endothelial cells and leukocyte tethering.