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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Heart. 2022 Feb 2;108(8):633–638. doi: 10.1136/heartjnl-2021-320356

Table II.

Risk of death associated with demographic and clinical characteristics

Univariable Multivariable
Reference/Risk HR (95% CI) P-value HR (95% CI) P-value
Age at enrollment (yrs) 9.7 yrs/15.0 yrs 1.26 (1.00; 1.58) 0.048 1.24 (0.99; 1.55) 0.066
Gender Female/Male 1.06 (0.79; 1.42) 0.720 1.10 (0.81; 1.49) 0.540
Distance nearest health unit (km) 1 km/5 km 1.16 (0.84; 1.61) 0.647 1.09 (0.79; 1.51) 0.864
Baseline complications No/Yes 2.06 (1.53; 2.78) <0.001 1.78 (1.31; 2.41) <0.001
Disease severity Mild/moderate 1.15 (0.36; 3.74) <0.001 0.92 (0.28; 3.00) <0.001
Severe 5.21 (2.15; 12.65) 4.58 (1.87; 11.23)
Intervention No/Yes 0.06 (0.02; 0.24) <0.001 0.05 (0.01; 0.21) <0.001

Abbreviations: HR, Hazard Ratio; CI, confidence interval; yrs, Years; KM, Kilometer

HRs and 95% CIs obtained from Cox proportional hazards regression. Interquartile range (25th vs. 75th percentile) HR is shown for continuous covariates. P-value for the Wald Chi-squared test for the model parameters(s).