Figure 2.

PET images of [¹⁸F] DOPA uptake distribution in rat brains. (A) Coronal (upper panel) and horizontal (lower panel) sections of each group were acquired 50−80 min after injection of ¹⁸F-DOPA. Left, middle, and right columns of each group represent ¹⁸F-DOPA uptake before the 6−OHDA lesion, after the 6−OHDA lesion, and at 4 and 8 weeks after transplantation, respectively. (B) Specific uptake ratios (SURs) of ¹⁸F−DOPA of the grafted striatum at different time points and under differ therapeutic regimen. * p < 0.05, *** p < 0.001 by Tukey’s multiple comparisons test, following two-way ANOVA. # p < 0.05 indicates comparison with the rVM + rhCDNF group with two-way ANOVA and Tukey’s post hoc test. The data represent mean ± SEM.