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. 2022 Jun 19;10(6):1446. doi: 10.3390/biomedicines10061446

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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PET images of [¹⁸F] FE−PE2I uptake distribution in rat brains. (A) Coronal (upper panel) and horizontal (lower panel) sections of each group were acquired 20–40 min after injection of ¹⁸F-FE-PE2I. Left, middle, and right columns of each group represent ¹⁸F-FE−PE2I uptake before the 6−OHDA lesion, after the 6-OHDA lesion, and at 4 and 8 weeks after transplantation, respectively. (B) Specific uptake ratios (SURs) of ¹⁸F−FE−PE2I of the grafted striatum at different time points and under differ therapeutic regimen. * p < 0.05, *** p < 0.001 by Tukey’s multiple comparisons test, following two-way ANOVA. ## p < 0.01 indicates comparison with the rVM + rhCDNF group with two-way ANOVA and Tukey’s post hoc test. The data represent mean ± SEM.