Table 1.
Description of characteristics and prognosis, for the population presenting a spinal solitary fibrous tumor, as diagnosed with positive STAT6 nuclear staining, for our series (n = 10) and a systematic review of the literature (n = 31).
| Characteristics | Our Series (n = 10) |
Literature Review (n = 31) |
Total (n = 41) |
|
|---|---|---|---|---|
| Population | ||||
| Sex | M | 6 (60%) | 14 (45%) | 20 (49%) |
| F | 4 (40%) | 17 (55%) | 21 (51%) | |
| Age, mean ± IC95 | 47 ± 8 | 45 ± 3 | 46 ± 4 | |
| Clinical and radiological presentations | ||||
| Spinal pain | 5 (50%) | 22 (76%) | 27 (69%) | |
| Radicular compression | 6 (60%) | 8 (28%) | 14 (36%) | |
| Spinal cord compression | 7 (70%) | 9 (31%) | 16 (41%) | |
| Urinary dysfunction | 4(40%) | 3 (10%) | 7 (18%) | |
| Motor dysfunction | 5 (50%) | 9 (29%) | 14 (34%) | |
| Sensory dysfunction | 4 (40%) | 6 (19%) | 10 (24%) | |
| Duration of symptoms (mo) | 10 ± 6 | 20 ± 12 | 17 ± 9 | |
| Tumor localization | Cervical | 5 (50%) | 7 (23%) | 12 (29%) |
| Thoracic | 4 (40%) | 17 (54%) | 21 (51%) | |
| Lumbar | 1 (10%) | 7 (23%) | 8 (20%) | |
| Tumor type | I extradural | 0 (0%) | 2 (14%) | 2 (9%) |
| II intradural | 7 (78%) | 8 (57%) | 15 (65%) | |
| III extra- and intradural |
2 (22%) | 4 (29%) | 6 (26%) | |
| Surgical and histological findings | ||||
| Complete resection | 7 (70%) | 22 (71%) | 29 (71%) | |
| Purely extramedullary tumor during surgery | 5 (50%) | 19 (68%) | 24 (63%) | |
| Histological grading | 1 | 1 (11%) | 6 (55%) | 7 (35%) |
| 2 | 5 (56%) | 0 (0%) | 5 (25%) | |
| 3 | 3 (33%) | 5 (45%) | 8 (40%) | |
| Post-operative management and outcome | ||||
| Primary adjuvant treatment | None | 6 (60%) | 14 (77%) | 30 (73%) |
| Radiotherapy | 4 (40%) | 7 (23%) | 11 (27%) | |
| Documented recurrence | 4 (40%) | 11 (32%) | 15 (37%) | |
| Time to first recurrence (mo) | 128 ± 116 | 49 ± 42 | 70 ± 47 | |