Table 1.
Background characteristics of the patients who underwent spinal metastasectomy.
| Groups | Total | Kidney | Thyroid | Low-Grade Sarcoma | Lung | Breast | p |
|---|---|---|---|---|---|---|---|
| Number of patients | 124 | 51 | 14 | 13 | 13 | 12 | - |
| Age (year), mean (SD) | 56.7 (10.7) | 59.2 (9.1) | 57.4 (9.5) | 51.5 (11.4) | 57.2 (8.2) | 56.8 (10.2) | - |
| Sex, female, n (%) | 51 (41.1) | 9 (17.6) | 12 (85.7) | 5 (38.5) | 7 (53.8) | 12 (100) | <0.05 |
| Level of metastatic lesion, n (%) | 0.48 | ||||||
| Thoracic | 82 (66.1) | 28 (54.9) | 11 (78.6) | 9 (69.2) | 9 (69.2) | 8 (66.7) | |
| Lumbar | 42 (33.9) | 23 (45.1) | 3 (21.4) | 4 (30.8) | 4 (30.8) | 4 (33.3) | |
| Preoperative ECOG PS, n (%) | 0.93 | ||||||
| 0–1 | 89 (71.8) | 35 (68.6) | 11 (78.6) | 9 (69.2) | 10 (76.9) | 9 (75.0) | |
| 2–3 | 35 (28.2) | 16 (31.4) | 3 (21.4) | 4 (30.8) | 3 (23.1) | 3 (25.0) | |
| Distinct metastatic sites, n (%) | 0.16 | ||||||
| One (only the spine) | 56 (45.2) | 16 (31.4) | 5 (35.7) | 6 (46.2) | 9 (69.2) | 5 (41.7) | |
| Two or more | 68 (54.8) | 35 (68.6) | 9 (64.3) | 7 (53.8) | 4 (30.8) | 7 (58.3) | |
| Location of other metastases, n (%) | |||||||
| Lung | 29 (23.4) | 15 (29.4) | 6 (42.9) | 4 (30.8) | 2 (15.4) | 0 (0) | 0.11 |
| Nonspinal bone | 32 (25.8) | 17 (33.3) | 4 (28.6) | 1 (7.7) | 1 (7.7) | 6 (50.0) | 0.06 |
| Lymph node | 13 (10.5) | 8 (15.7) | 0 (0) | 2 (15.4) | 1 (7.7) | 2 (16.7) | 0.56 |
| Other locations | 9 (7.3) | 8 (15.7) | 0 (0) | 1 (7.7) | 0 (0) | 0 (0) | 0.14 |
| Revised Tokuhashi score, mean (SD) | 11.5 (1.8) | 11.6 (1.3) #,¶,§ | 13.0 (1.6) †,\,¶ | 10.8 (1.2) #,¶,§ | 8.8 (1.7) †,#,\,§ | 13.7 (1.1) †,\,¶ | - |
| Tomita score, mean (SD) | 4.1 (1.3) | 3.7 (0.9) \,¶,§ | 3.1 (1.2) \,¶ | 5.6 (1.0) †,#,§ | 5.4 (0.8) †,#,§ | 2.5 (0.5) †,\,¶ | - |
| Preoperative systemic therapy, n (%) | 65 (52.4) | 28 (54.9) | 5 (35.7) | 3 (23.1) | 7 (53.8) | 9 (75.0) | 0.07 |
| Postoperative systemic therapy, n (%) | 85 (68.5) | 35 (68.6) | 10 (71.4) | 9 (69.2) | 9 (69.2) | 10 (83.3) | 0.88 |
†p < 0.05 versus the Kidney group, # p < 0.05 versus the Thyroid group, \ p < 0.05 versus the Low-grade sarcoma group,¶ p < 0.05 versus the Lung group, § p < 0.05 versus the Breast group. Abbreviations: ECOG PS, Eastern Cooperative Oncology Group performance status; SD, standard deviation.