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. 2022 Jun 12;12(6):820. doi: 10.3390/biom12060820

Figure 8.

Figure 8

Schwann cells hinder lymphatic vascular network formation in the presence of the pro-inflammatory cytokine TNF-α. LEC + ASC formed elongated and interconnected networks, even when stimulated with TNF-α; whereas the formation of lymphatic vessel-like structures in the LEC + ASC + SC cultures in the presence of TNF-α was hampered. The co-culture of only LECs and SCs did not show the formation of lymphatic tubes. Green—YFP-LECs, red—SCs stained against S100, blue—cell nuclei. Scale bars = 200 µm.