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Representative anti-inflammatory cytokines relevant to pro-tumoral and therapeutic trials for HNSCCs.
| Pro-Tumoral Activities | Therapeutic Trials | |
|---|---|---|
| IL-4 | Elevation in HNSCC patients (* 76, 77, 78, 79) | 81, 83 |
| Protection of tumor cells (80) | ||
| IL-10 | Elevation in HNSCC patients (85, 86) | |
| Abrogation of anti-tumoral immunity (87) | ||
| Enhancement of Treg and M2 macrophage (88) | ||
| Activation of TAM (89) |
* Numbers correspond to references in the text.
