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. 2022 Jun 10;14(12):2876. doi: 10.3390/cancers14122876

Figure 3.

Figure 3

Model of how electroporation may induce an immune response and elicit an abscopal effect when combined with immunotherapy. aT cell, activated T cell; CAF, cancer-associated fibroblast; CTLA-4, cytotoxic T lymphocyte antigen 4; DAMP, damage-associated molecular pattern; DC, dendritic cell; ECT, electrochemotherapy; IRE, irreversible electroporation; NK cell, natural killer cell; PD-1, programmed death receptor 1; PD-L1, programmed death-ligand 1; TAA, tumor-associated antigen; TLR, Toll-like receptor; TLR3-L, TLR3 ligand; Treg, regulatory T cell. Created with BioRender.com (accessed on 7 April 2022).