Table 1.
The clinicopathological characteristics of patients with pT3N0 colorectal cancer in the overall and review cohorts.
| Overall Cohort (n = 1634) | Review Cohort (n = 242) | |
|---|---|---|
| Age, mean ± SD, years | 63 ± 12 | 62 ± 12 |
| Sex | ||
| Male | 971 (59.6) | 136 (56.2) |
| Female | 663 (40.4) | 106 (43.8) |
| Location | ||
| Colon | 1166 (71.4) | 172 (71.1) |
| Rectum | 468 (28.6) | 70 (28.9) |
| Histologic differentiation | ||
| Well, moderately | 1520 (93.0) | 224 (92.6) |
| Poorly, mucinous, signet-ring cell | 53 (3.3) | 7 (2.9) |
| Unknown | 61 (3.7) | 11 (4.5) |
| Number of harvested LN, mean ± SD | 27 ± 11 | 28 ± 13 |
| <12 LN harvested | 17 (1.2) | 5 (2.1) |
| Lymphovascular invasion | 382 (23.4) | 26 (23.1) |
| Perineural invasion | 269 (16.5) | 31 (12.8) |
| Preoperative obstruction | 437 (26.7) | 82 (33.9) |
| Involved resection margin | 22 (1.3) | 6 (2.5) |
| MSI status | ||
| MSS | 1292 (79.1) | 199 (82.2) |
| MSI-L | 62 (3.8) | 0 |
| MSI-H | 169 (10.3) | 27 (11.2) |
| Unknown | 111 (6.8) | 16 (6.6) |
| Addition of adjuvant chemotherapy | 772 (47.2) | 127 (52.5) |
| Follow up duration, mean ± SD, months | 59 ± 23 | 61 ± 23 |
LN, lymph nodes; MSI, microsatellite instability; MSI-L, MSI low frequency; MSI-H, MSI high frequency; MSS, microsatellite stable; SD, standard deviation.