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. 2022 Jun 20;14(12):3028. doi: 10.3390/cancers14123028
BMDC bone-marrow-derived cells
CAF cancer-associated fibroblasts
DC dendritic cells
DTC disseminated tumor cells
CTL cytotoxic T lymphocytes
CTC circulating tumor cells
ECM extracellular matrix
EVs extracellular vesicles
FN fibronectin
HPCs hematopoietic progenitor cells
HSCs hepatic stellate cells
HUVECs human umbilical vein endothelial cells
LSECs liver sinusoidal endothelial cells
KCs Kupffer cells
KPC LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre genetically engineered mouse model of PDAC with the genotype ([46])
M-Fbs myeloid-derived fibroblasts
MDSCs myeloid derived suppressor cells
MIF macrophage migration inhibitory factor
MMP matrix metalloproteinase
NKs natural killer cells
PDAC pancreatic ductal adenocarcinoma
PDECs pancreatic ductal epithelial cells
PLGF placental growth factor
PSCs pancreatic stellate cells
SAA serum amyloid A
SDF-1 stromal cell-derived factor 1 (also known as CXCL12)
TAMs tumor-associated macrophages
TDSFs tumor-derived secreted factors
TGF-β transforming growth factor-β
TIMP-1 tissue inhibitor of metalloproteinases,
TME tumor microenvironment
Treg regulatory T cells
VEGF vascular endothelial growth factor