Combined curcumin (CUR) and luteolin (LUT) synergistically suppressed wound healing process in CL-188 cells: (A). Representative images of CL-188 cells treated with LUT 30 µM, CUR at 10 or 15 µM, and their combinations for 0 h, 24 h, and 72 h. (B). Bar graph showing area of wound closed in CL-188 cells using agents CUR at 10 or 15 µM, LUT at 30 µM, or combinations after 24 h. (C). Bar graph showing area of wound closed in CL-188 cells using agents CUR at 10 or 15 µM, LUT at 30 µM, or combinations after 72 h. Data were expressed in mean ± SEM of at least four independent experiments. *, Significant difference between DMSO and group, +, Significant difference between C10L30 and C10, L30 or C15L30 and C15 or L30; #, Significant difference between C10L30 and C15L30. *, + p < 0.05, **, ++, or ## p < 0.01, *** p < 0.001.