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Key characteristics of liquid biopsy targets for HNC.
| ctDNA | EXO | CTC | |
|---|---|---|---|
| Fluid Source | Blood; Saliva | Blood; Saliva | Blood |
| Concentration in Fluid | Moderate | High | Low |
| Sensitivity | Higher | Higher | Lower |
| Specificity | Higher | Lower | Variable |
| Applications | Screening; Prognosis; Treatment selection; Post-treatment surveillance |
Prognosis; Post-treatment surveillance |
Prognosis; Treatment selection |
