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. 2022 Jun 15;14(12):2963. doi: 10.3390/cancers14122963

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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HRQOL scores at baseline, after preoperative chemotherapy, after surgery, after postoperative chemotherapy, and at 12-month follow-up (from randomization). (a) Cognitive functioning. A higher score means better cognitive functioning. Interaction between time and group (ECX versus EOX): p = 0.629, (b) Physical functioning. A higher score means better physical functioning. Interaction between time and group (ECX versus EOX): p = 0.801, (c) Nausea/vomiting. A higher score means more symptoms of nausea/vomiting. Interaction between time and group (ECX versus EOX): p = 0.950, (d) Diarrhea. A higher score means more symptoms of diarrhea. Interaction between time and group (ECX versus EOX): p = 0.544, (e) QLQ C30 summary score. A higher score means a better overall score. Interaction between time and group (ECX versus EOX): p = 0.734.

HRQOL scores at baseline, after preoperative chemotherapy, after surgery, after postoperative chemotherapy, and at 12-month follow-up (from randomization). (a) Cognitive functioning. A higher score means better cognitive functioning. Interaction between time and group (ECX versus EOX): p = 0.629, (b) Physical functioning. A higher score means better physical functioning. Interaction between time and group (ECX versus EOX): p = 0.801, (c) Nausea/vomiting. A higher score means more symptoms of nausea/vomiting. Interaction between time and group (ECX versus EOX): p = 0.950, (d) Diarrhea. A higher score means more symptoms of diarrhea. Interaction between time and group (ECX versus EOX): p = 0.544, (e) QLQ C30 summary score. A higher score means a better overall score. Interaction between time and group (ECX versus EOX): p = 0.734.