Table 5.

Quality of Life. Mean changes in mean and effect sizes. SE = standard error. ES = effect sizes.

	T0–T1 Between-Group Difference			T0–T2 Between-Group Difference			T0–T3 Between-Group Difference			T0–T4 Between-Group Difference
	Mean Change (SE)	p	ES	Mean Change (SE)	p	ES	Mean Change (SE)	p	ES	Mean Change (SE)	p	ES
Cognitive Functioning	1.91 (2.78)	0.492	0.12	−0.61 (3.90)	0.876	−0.04	0.86 (4.36)	0.845	0.05	−3.98 (4.50)	0.379	−0.25
Physical Functioning	−5.63 (2.49)	0.025	−0.49	2.56 (3.32)	0.441	0.21	1.83 (3.57)	0.609	0.15	−2.08 (2.95)	0.482	−0.17
Nausea/Vomiting	6.34 (3.63)	0.083	0.38	2.45 (3.78)	0.518	0.15	1.66 (4.10)	0.686	0.10	0.18 (3.44)	0.959	0.01
Diarrhea	0.77 (4.48)	0.864	0.05	−17.68 (5.06)	0.001	−1.15	−13.98 (5.56)	0.013	−0.91	−12.30 (5.12)	0.018	−0.80
Corrected *	−1.13 (3.49)	0.365	−0.10	−18.84 (3.50)	<0.001	−1.60	−15.34 (3.66)	0.018	−1.30	−13.56 (3.95)	0.001	−1.15
QLQ C30 summary score	−2.36 (2.18)	0.280	−0.20	3.44 (2.95)	0.246	0.29	1.86 (3.02)	0.538	0.16	−1.50 (3.10)	0.629	−0.13

* corrected for tumor localization.