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. 2022 May 29;12(6):759. doi: 10.3390/biom12060759

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The anti-proliferation activity of temporin-PKE and its analogues against (a) HCT-116, (b) H838, (c) U251MG, (d) PC-3, and (e) H157 cells. PBS and 0.1% Triton X-100 were used as negative control and positive control, respectively. The results were analysed by two-way ANOVA and Dunnett’s multiple comparisons test, which compared different concentrations of peptides with the negative control group. The symbol **** indicates p < 0.0001. The error bar represents the SEM of the nine replicates in three tests (three replicates in each test).