Table 6.
Bacteria | MBIC 1/MBEC 2 (μM) | ||||||
---|---|---|---|---|---|---|---|
Temporin-PKE | 2K | K12 | 3K | 4K | i | 3i | |
S. aureus (ATCC 6538) | 2/256 | 2/64 | 4/128 | 2/64 | 32/128 | 2/128 | 64/128 |
E. coli (ATCC CRM 8739) | >512 | 64/>512 | 64/>512 | 16/512 | 128/>512 | >512 | >512 |
K. pneumoniae (ATCC 43816) | >512 | 128/>512 | 512/>512 | 32/512 | 256/>512 | >512 | >512 |
P. aeruginosa (ATCC CRM 9027) | >512 | >512 | >512 | 64/512 | 128/>512 | >512 | >512 |
MRSA (NCTC 12493) | 4/256 | 2/64 | 4/256 | 2/128 | 32/512 | 2/128 | 64/>512 |
E. faecalis (NCTC 12697) | 32/>512 | 16/>512 | 64/>512 | 4/>512 | 256/>512 | 4/>512 | 128/>512 |
1 The MBIC was the minimum concentration of the peptide showing no biofilm formation. 2 The MBEC is the lowest concentration of the peptide that can eradicate the mature biofilms, which had no biofilm in the well.