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Trends in the number of diagnosticsa performed among treated (n = 621; closed circles) and untreated patients (n = 3941; open circles) with CUP. B, biopsy; CUP, cancer-of-unknown-primary-origin; IHC, immunohistochemistry; IM, imaging. a Record of claim for a biopsy, immunohistochemistry, or imaging modality (computed tomography, positron emission tomography, magnetic resonance imaging) for any reason.
