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. 2022 Jun 10;11(12):1890. doi: 10.3390/cells11121890

Figure 2.

Figure 2

Camkk2 knockout increases tumor necrosis in castrated TRAMP mice. (A) Schema for mouse experiment. (B) % atrophied prostate and poorly differentiated or neuroendocrine (PD/NE) cancer (WT n = 10, KO n = 10). (C) prostate (WT n = 8, KO n = 7) and (D) tumor (WT n = 2, KO n = 2) weight normalized to kidney weight. (E) Representative images of prostates and tumors. (F) % coverage of viable vs necrotic cells in tumors (WT n = 2, KO n = 2) (Fisher’s exact test: p < 0.0001). ns = not significant by t test.